BEST NATURAL DHT BLOCKER

Notes:

• This webpage is a Reddit post on r/tressless titled “natural dht blockers vs artificial dht blockers” from 1 year and 5 months ago.
• The post asks whether it’s necessary to take Finasteride and Dutasteride when natural DHT blockers like pumpkin seeds, nettle tea, kale, and mushrooms can be consumed.
• A bot responds, directing the user to the wiki on Finasteride and telling them to see a doctor for questions about side effects.
• Some users suggest that the natural fallacy should not be believed as natural products are not necessarily healthier or more effective. They also question what reason there would be to believe a new natural DHT blocker would be any better than existing medications.
• Other users suggest that natural DHT blockers may not be as effective as Finasteride and Dutasteride and that hair loss is often too advanced to be treated by natural means alone.
• One user recommends trying natural DHT blockers first because they believe they are safer and have fewer side effects.
• Another user warns against taking Saw Palmetto, stating that it may cause serious side effects and has no measurable benefit. They also mention that they tried Saw Palmetto and did not find it effective.
• One user asks if they should wait until they are at least 25 years old to start taking Finasteride and Minoxidil because they fear that starting earlier will cause their body to develop tolerance to the medications.
• Users in the comments discuss the efficacy and safety of Finasteride and Dutasteride, as well as the side effects they have personally experienced.
• Other users share their personal experience with natural DHT blockers and how effective they have been.
• Some users discuss their hair regrowth progress on Finasteride and Minoxidil and share their personal opinions on the effectiveness of these medications.
• The comments section also includes discussions on the quality of hair regrowth and whether hair regrowth is permanent or temporary.

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• The article provides a list of effective hair loss treatments.
• Dutasteride, Finasteride, Minoxidil, Dermarolling, LLLT, PRP, Ketoconazole, and Scalp Massage are mentioned.
• Dutasteride is listed as the ultimate weapon against hair loss with an almost 100% response rate and produces better results than Finasteride.
• Finasteride is considered the most effective mainstream treatment as 86% of men keep their hair or grow more after 10 years of use.
• Minoxidil is the best product on the market for sparking new hair growth, but it does not address the underlying cause like Dutasteride and Finasteride.
• Dermarolling is undoubtedly effective according to many studies.
• LLLT has tangible benefits according to studies, and it can be used as a comb or helmet.
• PRP is an invasive and expensive treatment that works for many men, but it can be cost-prohibitive and inconvenient to use reliably.
• Ketoconazole has slight anti-inflammatory and antiandrogenic effects, and it may have a slight additive effect to Finasteride and Minoxidil.
• Scalp Massage is said to help with regrowth according to some studies.
• An anti-inflammatory diet (vegetarian) and stress management may also be helpful for preventing hair loss.
• In addition, hair transplants, hair systems, and SMP are options for those with significant hair loss.
• The most effective treatment depends on the severity of hair loss, and someone with slight thinning can start with Finasteride, whereas someone who is young and aggressively thinning may use Dopamine, Minoxidil, Dermarolling, and Ketoconazole.
• Other recommended treatments mentioned include Azelaic Acid, Zix, Castor Oil, Isotretinoin, and Stemoxydine.
• Biotin supplements and Krill oil capsules are also mentioned.
• The article has a comment section where users ask and provide recommendations and knowledge about hair loss treatments.
• Users provide information about the side effects of treatment and their personal experience with hair loss treatments.

• The webpage provides a meta-analysis of 17 hair loss prevention treatments, with 77 studies linked in the page.
• Purpose: To find effective FDA-approved alternatives to Finasteride and Minoxidil that either give poor results or unwanted side effects.
• Inclusion criteria: The compound should already be available on the market and must have a good quality human study with a control group that shows its efficacy. Plus, at least one human study using phototrichogram to assess the change in hair count, hair diameter, and eventually the conversion of vellus hair to terminal hair.
• Of the 17 effective treatments, several are DHT blockers:
  • Oral Dutasteride inhibits 5-alpha reductase, preventing the conversion of testosterone to DHT.
  • Topical Clascoterone (CB-03-01/Breezula) acts as a topical anti-androgen that inhibits the binding of DHT to androgen receptors on the scalp.
  • Other effective treatments are:
    • Oral/Topical Minoxidil that helps increase blood flow to the hair follicles.
    • Topical Finasteride that reduces DHT locally on the scalp.
    • Latanoprost 0.1% that alters hair cycles to shift from catagen to anagen phase.
    • Fluridil 2% that affects the production of VEGF to increase hair follicle size.
    • Alfatradiol 0.025% that inhibits the activity of enzymes in the scalp responsible for breaking down testosterone to DHT.
    • Redensyl 3% that stimulates stem cell proliferation and helps hair follicles enter the anagen phase.
    • Adenosine that stimulates hair growth at the root level.
    • Topical Dutasteride that inhibits 5-alpha-reductase directly on the scalp.
    • Low Level Laser Therapy (LLLT) that uses light energy to stimulate hair follicles to grow.
    • Platelet Rich Plasma (PRP) that uses the patient’s own blood plasma to stimulate hair growth.
    • Stemoxydine 5% that simulates hypoxia to wake up the hair follicles from dormancy.
    • Topical 1% Procyanidin B-2 that blocks PGD2 and stimulates hair growth.
    • Topical Spironolactone 1% that blocks the androgen receptor on hair follicles.
    • Oral Procyanidin B-2 that blocks

• W is a website that provides a list of various ingredients that inhibit DHT production.
• Some of the ingredients on the list are oils, while others are non-oil based ingredients such as copper peptides, green tea, and zinc.
• Almond/sweet almond oil is listed as an inhibitor due to the oleic and linoleic acid content.
• Aloe vera is listed due to the linoleic acid content.
• Amla oil is listed due to the linoleic and oleic acid content.
• Argan oil is listed due to the oleic and linoleic acid content.
• Apricot kernel oil is listed due to the oleic and linoleic acid content.
• Avocado oil is listed due to the oleic and linoleic acid content, while beta-sitosterol is a DHT inhibitor found in consumable avocado.
• Babassu oil is listed due to the high lauric acid content, with lower levels of oleic and linoleic acid.
• Baobab seed oil is listed due to the linoleic and oleic acid content.
• Black cumin seed oil is listed due to the linoleic acid content.
• Black currant seed oil is listed due to the linoleic and oleic acid content.
• Black raspberry seed oil is listed due to the linoleic and oleic acid content.
• Burdock seed oil is listed due to the linoleic and oleic acid content.
• Camelina oil is listed due to the oleic and linoleic acid content.
• Carrot seed oil is listed due to the oleic and linoleic acid content.
• Cherry kernel oil is listed due to the oleic and linoleic acid content.
• Chia seed oil is listed due to the linoleic and oleic acid content.
• Chokeberry seed oil is listed due to the linoleic and oleic acid content.
• Cloudberry seed oil is listed due to the linoleic and oleic acid content.
• Cocoa butter is listed due to the oleic acid content.
• Coconut oil’s lauric and oleic acid content makes it a DHT inhibitor in consumable form, while refined coconut oil has lower levels of these two acids and thus is not listed here.
• Copper peptides are listed without specific information about their mechanism as a DHT inhibitor.
• Corn oil is listed due to the linoleic acid content.
• Cottonseed oil is listed due to the lin

• The post on the r/FemaleHairLoss subreddit discusses natural DHT blockers and their effectiveness
• The post asks whether natural DHT blockers have worked for anyone.
• Spironolactone is a prescription medication that many with hair loss try, but it is not always an option for everyone.
• Saw Palmetto, Stinging Nettle, Pumpkin Seed oil, Rosemary oil, and other natural DHT blockers are discussed.
• One user has experienced a decrease in shedding after using a combination of topical rosemary oil and saw palmetto (16 karma).
• This user applies the rosemary and saw palmetto about 5-6 times per week.
• Another user mentions taking saw palmetto and spearmint tea capsules (10 karma).
• A third user uses a pre-made topical solution with saw palmetto, pumpkin seed, rosemary, and other ingredients but isn’t sure if it is working yet (4 karma).
• Some users discuss the impact of telogen effluvium on shedding and whether DHT blockers are effective for intense shedding caused by it.
• One user mentions taking vitamin D, flaxseed oil, green tea, and eating soy to control shedding (6 karma).
• Another user uses a rosemary-based organic shampoo (3 karma).
• Users ask for advice on how to dilute rosemary oil and saw palmetto for topical use.
• A user mentions using a brand called Moogoo talc-free dry shampoo (1 karma).
• A user discusses getting skin irritation from a rosemary-based topical solution and asks about other options (1 karma).
• Another user mentions using a natural solution that combines rosemary oil, lavender oil, and peppermint oil on the scalp (4 karma).
• Users discuss the possible negative side effects of taking saw palmetto orally.
• Several users ask for links to the products mentioned and sources for the remedies.
• Many users share their individual experiences and offer encouragement and advice to others.

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• Title of the post: “Any experience on Natural DHT blocker?”
• The post is from 2 years ago and was posted in the subreddit r/tressless.
• The post author asks for people’s experiences using natural DHT blockers, specifically saw palmetto extract, pumpkin seed oil, and stinging nettle extract.
• A user comments that a DHT inhibitor works to slow hair loss regardless of if it’s natural or not, and that saw palmetto may be able to halt mild hair loss by itself.
• Another user responds to the question of why the post author is specifically asking for “natural” DHT blockers, stating that the side effects of DHT blockers come from the inhibition of DHT itself, and it doesn’t matter how it’s blocked.
• A female user asks how to notice if she’s suffering from AGA (androgenetic alopecia), as it’s rare in females and harder to distinguish from other causes.
• Another user responds that the only way for a woman to fight DHT directly is on the scalp, and suggests RU58841 and Ketoconazole as potential options.
• The same user recommends minoxidil and ketoconazole, and suggests that liquid minoxidil may be more effective than foam, which resulted in more shedding for them.
• Another user suggests coconut as an alternative, and recommends coconut milk-based smoothies
• A user shares their experience using saw palmetto for months with no real regrowth, and is now experimenting with low dose topical finasteride.
• Another user recommends high potent saw palmetto in 480mg 6x strength, and shares that they’ve been using natural blockers for 7 years with success.
• A user suggests that natural DHT blockers can work well as additives to finasteride for increased effectiveness.
• A user simply suggests taking finasteride to combat hair loss, without mentioning the use of natural DHT blockers.
• One user states simply that natural DHT blockers don’t work, with a negative karma rating.

Here are my notes:

• The original poster asked for natural DHT blockers that are effective other than Finasteride.
• Saw palmetto is commonly regarded as an ineffective natural DHT blocker, and various other natural DHT blockers are discussed, such as:
  • Curcumin in turmeric extracts, which may inhibit the 5-AR enzyme and decrease DHT. It has been shown to have inhibitory effects on androgens as per studies conducted on BPH.
  • Stinging nettle tea, which a user had been drinking for a year with no noticeable effect.
  • Azeliac acid and Reishi Mushroom, which have been shown to inhibit 5 alpha reductase in vitro but have not been proven to slow down the miniaturization process or be of benefit.
  • Alfatradiol (a topical treatment) and Revivogen (a hair loss treatment) which may help according to reviews on HairLossTalk.
  • Zinc and vitamin B6, in a topical mixture known as the Zix, which is popular but was not personally used by a user.
• There are conflicting opinions on the effectiveness of natural DHT blockers and other treatments as many state no noticeable difference. Some state natural treatments may slow down the miniaturization process, but the hair loss continues. A few users have had marginal benefit with treatments like Revivogen.
• A user suggests trying diet supplements and lowering DHT through diet, with mixed results.
• Some users point out the misconception that natural DHT blockers may not cause side effects. DHT is an unnatural thing to block, so it’s irrelevant if it’s a natural or pharmaceutical blocker.
• A few users strongly recommend Finasteride as the most effective treatment, suggesting lower doses to reduce side effects.
• Curcumin is shown to be non-toxic, unlike Finasteride, which can have adverse effects such as erectile dysfunction and infertility.
• An enzyme called Aldo‐Keto reductase 1C2 (AKR1C2), whose increase may support the decrease of DHT when curcumin is supplemented, is mentioned.

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